Mycobacterium tuberculosis as a cause of mandibular osteomyelitis in a young woman: A case report

被引：3
作者：
Tellez-Rodriguez J. [1 ]
Lopez-Fernandez R. [1 ]
Rodriguez-Jurado R. [2 ]
Moreno-Sandoval H.N. [3 ]
Martinez-Perez F. [4 ]
Gonzalez-Barrios J.A. [3 ]
机构：
[1] Departamento de Cirugía Maxilofacial, Insurgentes sur 3700, Letra C, Col. Insurgentes Cuicuilco, Mexico City
[2] Departamento de Anatomía Patológica Del Instituto Nacional de Pediatría, Insurgentes sur 3700, Letra C, Col. Insurgentes Cuicuilco, Mexico City
[3] Laboratorio de Medicina Genómica, Hospital Regional 1o. de Octubre, Avenida Instituto Politécnico Nacional 1669, Mexico City
[4] Laboratorio de Genómica de Celomados, Grupo de Investiagición en Microbiología y Genética, Escuela de Biología, Universidad Industrial de Santander, Carrera 27, Calle 9, Bucaramanga, Santander
来源：
Journal of Medical Case Reports | / 10卷 / 1期
关键词：
Case report; Jaw; Mycobacterium tuberculosis; Osteomyelitis; Tuberculosis;
D O I：
10.1186/s13256-016-1118-x
中图分类号：
学科分类号：
摘要：
Background: Tuberculosis is considered an emerging disease worldwide; in the last 10 years, its incidence has increased to more than 9.6 million cases of active tuberculosis. In 2014, it resulted in 1.5 million patient deaths. However, oral presentation with bone involvement occurs in less than 3% of all reported cases and rarely arouses clinical suspicion on initial presentation. Case presentation: A 15-year-old Mexican girl who had a previous diagnosis of neurofibromatosis presented to our hospital with pain and swelling in the region of the left mandibular body since November 2011. A clinical examination revealed pain in the mandibular region, a mass of soft consistency that seemed to involve bone, and a fistula with discharge of intraoral purulent material. Additionally, tachycardia and hyperthermia were observed. The left submental and submandibular regions had a 12-cm-diameter swelling, which was well-delineated and nonerythematous. The final diagnosis was established by real-time polymerase chain reaction. Conclusions: The final diagnosis of rare cases of tuberculous osteomyelitis in the jaw can be established by deoxyribonucleic acid (DNA) identification of Mycobacterium tuberculosis in the lesion. Simple and fast complementary diagnosis by real-time polymerase chain reaction is a fundamental approach to establishing early and effective pharmacological and surgical treatment. © 2016 The Author(s).
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