A study of the synthesis of triazoles using microwave irradiation

被引：0
|
作者：
Kenneth A. Savin
Michael Robertson
Doug Gernert
Steven Green
Erik J. Hembre
Jessie Bishop
机构：
[1] Eli Lilly and Company,Lilly Research Laboratories
来源：
Molecular Diversity | 2003年 / 7卷
关键词：
[3+2] cycloaddition; flow-through reaction; microwave irradiation; montmorillonite (K-10) clay; triazole;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Herein we describe the conversion of a known [3+2] cycloaddition reaction between an azide and an acetylene from a thermally promoted reaction to a microwave assisted process. Modification of conditions including concentration, temperature, solvent type and time were investigated. This methodology study led us to use high concentration and high temperatures to achieve the desired fast reaction times and high yields.
引用
收藏
页码：171 / 174
页数：3
相关论文
共 50 条
  • [1] A study of the synthesis of triazoles using microwave irradiation
    Savin, Kenneth A.
    Robertson, Michael
    Gernert, Doug
    Green, Steven
    Hembre, Erik J.
    Bishop, Jessie
    MOLECULAR DIVERSITY, 2003, 7 (2-4) : 171 - 174
  • [2] Improvement in the synthesis of metallophthalocyanines using microwave irradiation
    Burczyk, A
    Loupy, A
    Bogdal, D
    Petit, A
    TETRAHEDRON, 2005, 61 (01) : 179 - 188
  • [3] Synthesis of isopropyl salicylate using microwave irradiation
    Li, YT
    Yin, YW
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2002, 22 (10) : 750 - 753
  • [4] An improved synthesis of substituted benzolblthiophenes using microwave irradiation
    Allen, D
    Callaghan, O
    Cordier, FL
    Dobson, DR
    Harris, JR
    Hotten, TM
    Owton, WM
    Rathmell, RE
    Wood, VA
    TETRAHEDRON LETTERS, 2004, 45 (52) : 9645 - 9647
  • [5] Microwave assisted synthesis and antimicrobial screening of fused triazoles
    Shiradkar, Mahendra
    Pandit, Unnat
    Akula, Kalyan Chakravarthy
    Maheta, Abhay
    Kumar, Gorentla Venkata Suresh
    ARKIVOC, 2006, : 141 - 154
  • [6] Hydroxyapatite synthesis using microwave irradiation during the crystallization step
    Rivera, J. A.
    Fetter, G.
    Bosch, P.
    MATERIA-RIO DE JANEIRO, 2010, 15 (04): : 506 - 515
  • [7] Simplified approach to the regiospecific synthesis of trichloromethylpyrazolines using microwave irradiation
    Martins, Marcos A. P.
    Muraro, Paulo
    Beck, Paulo
    Machado, Pablo
    Frizzo, Clarissa P.
    Zanatta, Nilo
    Bonacorso, Helio G.
    SYNTHETIC COMMUNICATIONS, 2008, 38 (20) : 3465 - 3476
  • [8] Solid supported synthesis of novel γ-lactams using microwave irradiation
    Kidwai, M
    Mishra, AD
    Venkataramanan, R
    OXIDATION COMMUNICATIONS, 2003, 26 (04): : 586 - 590
  • [9] Rapid synthesis of hollow CTS nanoparticles using microwave irradiation
    Wang, Wei
    Shen, Honglie
    Li, Jinze
    MATERIALS LETTERS, 2013, 111 : 5 - 8
  • [10] Greener and expeditious synthesis of bioactive heterocycles using microwave irradiation
    Polshettiwar, Vivek
    Varma, Rajender S.
    PURE AND APPLIED CHEMISTRY, 2008, 80 (04) : 777 - 790
12345