TLC Analysis of Twelve Different Salts of Oxime HI-6 — Reactivator of Nerve Agent Inhibited AChE

被引:0
作者
Daniel Jun
Petr Stodulka
Martina Hrabinova
Miroslav Pohanka
Bohuslav Doleza
Kamil Kuca
机构
[1] University of Defence,Center of Advanced Studies, Faculty of Military Health Sciences
[2] Vakos XT a.s.,undefined
来源
JPC – Journal of Planar Chromatography – Modern TLC | 2011年 / 24卷
关键词
TLC; HI-6; Salt; Oxime; Antidote; Reactivation;
D O I
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学科分类号
摘要
Four thin-layer chromatographic (TLC) methods for identification of twelve bisquaternary acetylcholinesterase reactivator HI-6 salts (sulfate, chloride, acetate, bromide, phosphate, mesylate, tartrate, iodide, malonate, salicylate, maleinate, and tosylate) are described. By use of TLC, particular E and Z isomers of each salt on the oxime group were also separated. These TLC methods could be of high interest for rapid identification of each salt and for purity control.
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页码:105 / 107
页数:2
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