Glutamine Synthetase-Containing Cells of the Dorsal Root Ganglion at Different Stages of Rat Ontogeny

被引:0
作者
E. A. Kolos
D. E. Korzhevskii
机构
[1] Institute of Experimental Medicine,Laboratory of Functional Morphology of the Central and Peripheral Nervous System, Department of General and Special Morphology
来源
Russian Journal of Developmental Biology | 2018年 / 49卷
关键词
satellite cells; dorsal root ganglion; glutamine synthetase; ontogeny;
D O I
暂无
中图分类号
学科分类号
摘要
In the present study, formation, location, and morphological features of glutamine synthetaseimmunopositive cells of the dorsal root ganglion (DRG) at different stages of prenatal and postnatal development of the rat was examined. It was demonstrated that small differentiating satellite cells containing glutamine synthetase were observed in the DRG close to sensory neurons on embryonic day 18. On embryonic day 19, the forming immunopositive glial cells were located around developing neurons of the DRG in accordance with topography, which is observed in newborn and adult animals. The averaged number of satellite cells per sensory neuron in mature and aging rats was calculated and it was found that this index did not change during aging.
引用
收藏
页码:179 / 183
页数:4
相关论文
共 73 条
[11]  
Carozzi V.A.(2002)Glutamate and the presynaptic control of spinal sensory transmission Neuroscientist 8 89-71
[12]  
Canta A.(2010)Can satellite glial cells be therapeutic targets for pain control? Neuron. Glia Biol. 6 63-76
[13]  
Oggioni N.(2016)Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation Acta Neuropathol. Commun. 4 46-1436
[14]  
Cecchini T.(2013)Vimentin and s100 protein in the cells of forming sensory node of spinal nerve Morfologiya 3 74-151
[15]  
Ferri P.(2013)Evidence for glutamate as a neuroglial transmitter within sensory ganglia PLoS One 8 e68312-3358
[16]  
Ciaroni S.(2013)Temporospatial expression and cellular localization of glutamine synthetase following traumatic spinal cord injury in adult rats Mol. Med. Rep. 7 1431-211
[17]  
Costa F.A.L.(2003)Age-related quantitative changes in mitochondria of satellite cell sheaths enveloping spinal ganglion neurons in the rabbit Brain Res. Bull. 61 147-70
[18]  
Moreira Neto F.L.(2007)The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain J. Neurosci. Res. 85 3347-1017
[19]  
Donkelaar H.J.(2002)Glutamine-, glutamine synthetase-, glutamate dehydrogenase-and pyruvate carboxylase-immunoreactivities in the rat dorsal root ganglion and peripheral nerve Brain Res. 945 202-463
[20]  
Gong K.(2002)Levels of amino acid neurotransmitters during neurogenesis and in histotypic cultures of mouse spinal cord Dev. Neurosci. 24 59-597