The realized niche of adult neural stem cells

被引:0
作者
Christian Nern
Stefan Momma
机构
[1] University of Frankfurt,Institute of Neurology (Edinger Institute)
来源
Stem Cell Reviews | 2006年 / 2卷
关键词
Neural stem cell; stem cell; niche; subventricular zone; neurogenesis; neurosphere; extracellular matrix; vascular niche;
D O I
暂无
中图分类号
学科分类号
摘要
This review gives an overview of current issues concerning the application of the concept of the stem cell niche to the adult mammalian brain. It describes how the niche manifests itself at different structural levels as well as the main applications that are influenced by this concept. Finally, special regard is given to what is known for the adult human brain and how far the findings from lower animals can be applied in harnessing the regenerative potential of stem cells for therapy.
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页码:233 / 240
页数:7
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