Testosterone induces renal tubular epithelial cell death through the HIF-1α/BNIP3 pathway

[1] Pearle MS(2005)Urologic diseases of America P: urologic diseases in America project: urolithiasis J Urol 173 848-857

[2] Calhoun EA(2014)Androgen receptor enhances kidney stone-CaOx crystal formation via modulation of oxalate biosynthesis and oxidative stress Mol Endocrinol 28 1291-1303

[3] Curhan GC(2013)Serum estradiol and testosterone levels in kidney stones disease with and without calcium oxalate components in naturally postmenopausal women PLoS ONE 8 e75513-120

[4] Liang L(2008)Mechanism of calcium oxalate renal stone formation and renal tubular cell injury Int J Urol 15 115-178

[5] Li L(2016)Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis Nat Commun 7 10274-1448

[6] Tian J(2001)Intratubular crystallization of calcium oxalate in the presence of membrane vesicles: an in vitro study Kidney Int 59 169-6673

[7] Lee SO(2000)BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites J Biol Chem 275 1439-124

[8] Dang Q(2001)HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors Cancer Res 61 6669-402

[9] Huang CK(2017)Expanding perspectives on the significance of mitophagy in cancer Semin Cancer Biol 47 110-1027

[10] Yeh S(2014)BNIP3 upregulation by ERK and JNK mediates cadmium-induced necrosis in neuronal cells Toxicol Sci 140 393-5454

[1] Pearle MS(2005)Urologic diseases of America P: urologic diseases in America project: urolithiasis J Urol 173 848-857

[2] Calhoun EA(2014)Androgen receptor enhances kidney stone-CaOx crystal formation via modulation of oxalate biosynthesis and oxidative stress Mol Endocrinol 28 1291-1303

[3] Curhan GC(2013)Serum estradiol and testosterone levels in kidney stones disease with and without calcium oxalate components in naturally postmenopausal women PLoS ONE 8 e75513-120

[4] Liang L(2008)Mechanism of calcium oxalate renal stone formation and renal tubular cell injury Int J Urol 15 115-178

[5] Li L(2016)Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis Nat Commun 7 10274-1448

[6] Tian J(2001)Intratubular crystallization of calcium oxalate in the presence of membrane vesicles: an in vitro study Kidney Int 59 169-6673

[7] Lee SO(2000)BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites J Biol Chem 275 1439-124

[8] Dang Q(2001)HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors Cancer Res 61 6669-402

[9] Huang CK(2017)Expanding perspectives on the significance of mitophagy in cancer Semin Cancer Biol 47 110-1027

[10] Yeh S(2014)BNIP3 upregulation by ERK and JNK mediates cadmium-induced necrosis in neuronal cells Toxicol Sci 140 393-5454