Cyanoethylation and carboxyethylation of 5-benzofuryl-4-substituted 4H-1,2,4-triazole-3-thiols

被引:0
作者
M. A. Kaldrikyan
N. S. Minasyan
机构
[1] Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of Armenia,Mnjoyan Institute of Fine Organic Chemistry
[2] National Academy of Sciences of the Republic of Armenia,Molecular Structure Research Center
来源
Russian Journal of General Chemistry | 2017年 / 87卷
关键词
benzofuryl-1,2,4-triazole-3-thiol; acrylonitrile; cyanoethylation; acrylic acid; carboxyethylation; -alkylation;
D O I
暂无
中图分类号
学科分类号
摘要
Base-catalyzed reactions of 5-benzofuryl-4-substituted 4H-1,2,4-triazole-3-thiols with acrylonitrile and acrylic acid afforded 2-(2-cyanoethyl)- or 2-(2-carboxyethyl)triazoline-3-thiones. Attempts to obtain the corresponding sulfanyl derivatives failed.
引用
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页码:1317 / 1320
页数:3
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共 58 条
  • [1] Sidwell R.W.(1972)undefined Science 177 705-undefined
  • [2] Hofman J.H.(2005)undefined Antiviral Res. 68 10-undefined
  • [3] Khore G.P.(2001)undefined Br. J. Pharmacol. 133 1029-undefined
  • [4] Allen L.B.(1999)undefined Endocrine-Related Cancer 6 259-undefined
  • [5] Witkowski J.T.(2015)undefined Pharm. Chem. J. 49 251-undefined
  • [6] Robins R.K.(2014)undefined Russ. J. Org. Chem. 50 736-undefined
  • [7] Sidwell R.W.(2012)undefined Pharm. Chem. J. 45 705-undefined
  • [8] Bailey K.W.(2009)undefined Pharm. Chem. J. 43 645-undefined
  • [9] Wong M.H.(2009)undefined Pharm. Chem. J. 43 242-undefined
  • [10] Bernard D.L.(2011)undefined Pharm. Chem. J. 45 211-undefined