Risk stratification of sudden cardiac death in Brugada syndrome: an updated review of literature

被引:0
作者
Charmake Darar
El-Azrak Mohammed
Boutaybi Mohammed
El Ouafi Noha
Bazid Zakaria
机构
[1] Oujda/Mohammed I University,Departement of Cardiology, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy
[2] Mohammed VI University Hospital,Epidemiological Laboratory of Clinical Research and Public Health
来源
The Egyptian Heart Journal | / 74卷
关键词
Brugada syndrome; Sudden cardiac death; Risk stratification; Ventricular fibrillation; Channelopathy;
D O I
暂无
中图分类号
学科分类号
摘要
Brugada syndrome is a rare but serious inherited heart disease that causes sudden cardiac death by polymorphic ventricular tachycardia or ventricular fibrillation. It is an autosomal dominant genetic disease that usually occurs in patients in their forties with a structurally normal heart. Electrically, it manifests by ST elevation segment ≥ 2 mm of at least one right precordial lead (V1 and/or V2). Stratification of sudden cardiac death in Brugada syndrome is not always easy and constitutes a real challenge for the practitioner. In this review, we will present the current state of knowledge for arrhythmic risk stratification and the prevention of sudden cardiac death that can result from this syndrome.
引用
收藏
相关论文
共 153 条
  • [1] Brugada P(1992)Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report J Am Coll Cardiol 20 1391-1396
  • [2] Brugada J(2013)HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes : document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013 Heart Rhythm Off Heart Rhythm 10 1932-1963
  • [3] Priori SG(2002)Proposed diagnostic criteria for the Brugada syndrome: consensus report Circulation 106 2514-2519
  • [4] Wilde AA(2013)Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death Nat Genet 45 1044-1049
  • [5] Horie M(2012)Risk stratification in Brugada syndrome: results of the PRELUDE (PRogrammed ELectrical stimUlation preDictive valuE) registry J Am Coll Cardiol 59 37-45
  • [6] Wilde AA(2010)An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing Heart Rhythm 7 33-46
  • [7] Antzelevitch C(2018)Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing Europace 20 f64-71
  • [8] Borggrefe M(2015)Time-dependent responses to provocative testing with flecainide in the diagnosis of Brugada syndrome Heart Rhythm 12 350-357
  • [9] Bezzina CR(2017)Sodium-channel blocker challenge in the familial screening of Brugada syndrome: safety and predictors of positivity Heart Rhythm 14 1442-1448
  • [10] Barc J(2005)Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association Circulation 111 659-670