Leflunomide in systemic onset juvenile idiopathic arthritis

被引:0
作者
Afsana Jahan
Vivek Dewan
Tribhuvan Pal Yadav
机构
[1] Dr Ram Manohar Lohia hospital,Department of Paediatrics, Post Graduate Institute of Medical Education and Research
来源
Indian Pediatrics | 2012年 / 49卷
关键词
Systemic onset juvenile idiopathic arthritis; leflunomide;
D O I
暂无
中图分类号
学科分类号
摘要
Methotrexate, the mainstay of treatment in Juvenile idiopathic arthritis, might not be effective in a few patients of polyarticular and systemic onset juvenile idiopathic arthritis. Use of biologicals like TNF-α blockers, the next line of preferred drugs is constrained by the high cost. We successfully used leflunomide in four patients.
引用
收藏
页码:750 / 752
页数:2
相关论文
共 21 条
  • [1] Fox R.I.(1998)Mechanism of action of leflunomide in rheumatoid arthritis J Rheumatol (Suppl.) 53 20-26
  • [2] Silverman E.(2005)Leflunomide or methotrexate for juvenile rheumatoid arthritis NEJM. 352 655-666
  • [3] Mouy R.(2005)Long term open label preliminary study of safety and efficacy of leflunomide in patients with polyarticular-course in juvenile rheumatoid arthritis Arthritis Rheum. 52 554-562
  • [4] Spiegel L.(2003)Leflunomide for the treatment of rheumatoid arthritis: A systematic review and metaanalysis J Rheumatol. 30 1182-1190
  • [5] Jung L.K.(2010)Effectiveness of leflunomide in patients with juvenile idiopathic arthritis in clinical practice J Rheumatol. 37 1763-1767
  • [6] Saurenmann R.K.(undefined)undefined undefined undefined undefined-undefined
  • [7] Lahdenne P.(undefined)undefined undefined undefined undefined-undefined
  • [8] Silverman E.(undefined)undefined undefined undefined undefined-undefined
  • [9] Spiegel L.(undefined)undefined undefined undefined undefined-undefined
  • [10] Hawkins D.(undefined)undefined undefined undefined undefined-undefined