Influence of the aggregation, concentration, and viscosity on the nanomagnetism of iron oxide nanoparticle colloids for magnetic hyperthermia

被引：0
作者：
David Cabrera
Julio Camarero
Daniel Ortega
Francisco J. Teran
机构：
[1] Ciudad Universitaria de Cantoblanco,IMDEA Nanociencia
[2] Universidad Autónoma de Madrid,Dpto. Física Materia Condensada and Instituto “Nicolás Cabrera”
[3] University College London,Institute of Biomedical Engineering
[4] Ciudad Universitaria de Cantoblanco,Unidad Asociada de Nanobiotecnología, CNB
来源：
Journal of Nanoparticle Research | 2015年 / 17卷
关键词：
Nanomagnetism; Magnetic iron oxide nanoparticles; Magnetic hyperthermia; Dipolar interactions; Aggregation; Viscosiy; Cell internalization; Bioinspired nanomaterials;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Iron oxide nanoparticles have become ubiquitous in many biomedical applications, acting as core elements in an increasing number of therapeutic and diagnostic modalities. These applications mainly rely on their static and dynamic magnetic properties, through which they can be remotely actuated. However, little attention has been paid to understand the variation of the magnetic response of nanoparticles inside cells or tissues, despite of the remarkable changes reported to date. In this article, we provide some hints to analyze the influence of the biological matrix on the magnetism of iron oxide nanoparticles. To this aim, we propose the assessment of the heating efficiency of magnetic colloids against nanoparticle aggregation, concentration, and viscosity in order to mimic the fate of nanoparticles upon cell internalization.
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