Post-transplantation lymphoproliferative disorder (PTLD) twenty years after heart transplantation: a case report and review of the literature

被引：0
作者：
Petros D. Grivas
机构：
[1] Hahnemann University Hospital/Drexel University College of Medicine,Department of Internal Medicine
来源：
Medical Oncology | 2011年 / 28卷
关键词：
Post-transplantation lymphoproliferative disorder; Diffuse large B-cell lymphoma; Epstein–Barr virus; Rituximab; Chemotherapy; Immunosuppression;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We report a 62-year-old man who developed biopsy-proven post-transplantation lymphoproliferative disorder (PTLD) 20 years after receiving a heart transplant while being treated with immunosuppressive agents. The patient presented with large retroperitoneal and intestinal wall masses that caused partial gastrointestinal stenosis. Monoclonal antibody against CD20 in conjunction with chemotherapy and tapering of the immunosuppressive regimen was instituted, resulting in objective response of the disease bulk. To the best of our knowledge, this is the second reported case of PTLD 20 years after heart transplantation.
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页码：829 / 834
页数：5
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