Distal left circumflex coronary artery flow reserve recorded by transthoracic Doppler echocardiography: A comparison with Doppler-wire

被引:9
作者
Auriti A. [1 ]
Pristipino C. [2 ]
Cianfrocca C. [1 ]
Granatelli A. [2 ]
Guido V. [1 ]
Pelliccia F. [2 ]
Greco S. [1 ]
Richichi G. [2 ]
Santini M. [1 ]
机构
[1] Department of Cardiovascular Disease, Echocardiography Unit, S. Filippo Neri Hospital, Rome
[2] Coronary Intervention Unit, ROMA (Ricerche Orientate Sulla Malattia Aterosclerotica) Core Lab., S. Filippo Neri Hospital, Rome
关键词
Left Anterior Descend; Coronary Flow Reserve; Inferior Myocardial Infarction; Obtuse Marginal; Impaired Coronary Flow Reserve;
D O I
10.1186/1476-7120-5-22
中图分类号
学科分类号
摘要
Background. Coronary flow reserve (CFR) recording by means of transthoracic echocardiography (TTDE) in all the main distal coronary arteries is a challenge for advanced echocardiography. Validation studies of TTDE versus Doppler-wire (DW) recordings are available for Left Anterior Descending artery (LAD) and the Posterior Descending coronary artery (PD), but lacking for the more technically challenging Left Circumflex coronary artery (LCx). Aim. To evaluate the reliability of TTDE in assessing CFR in LCx when compared to the intracoronary Doppler flow-wire gold standard. Methods. we evaluated 5 patients (age = 60 ± 9 years, 5 males) on LCx by TTDE and invasive CFR assessment. TTDE recording was performed using a low-frequency probe, with a four-chamber as a guiding 2D view. The 2 tests were performed on different days and in random order within 48 hours in a blind fashion. Vasodilator stimulus was adenosine, intravenously (140 γ/kg/min × 3-6 min) for TTDE and intracoronary (40 γ bolus) for DW recordings. Results. CFR values on LCx ranged from 1.9 to 2.8 for DW, and from 2.0 to 3.0 for TTDE, with an overall correlation of R = 0,85 (p = 0,06); normal (CFR > 2.5) or abnormal (CFR < 2.5) value was concordantly identified by the 2 techniques in 4 out 5 cases (80%). Conclusion. CFR of LCx artery can be obtained noninvasively with TTDE. © 2007 Auriti et al; licensee BioMed Central Ltd.
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