Panton-Valentine leukocidin genes and staphylococcal chromosomal cassette mec types amongst Finnish community-acquired methicillin-resistant Staphylococcus aureus strains, 1997–1999

被引:0
作者
M. Kardén-Lilja
S. Ibrahem
J. Vuopio-Varkila
S. Salmenlinna
O. Lyytikäinen
L. Siira
A. Virolainen
机构
[1] National Public Health Institute,Department of Bacterial and Inflammatory Diseases
[2] University of Helsinki,Haartman Institute, Department of Bacteriology and Immunology
[3] National Public Health Institute,Department of Infectious Disease Epidemiology
来源
European Journal of Clinical Microbiology & Infectious Diseases | 2007年 / 26卷
关键词
Polymerase Chain Reaction Assay; Multiplex Polymerase Chain Reaction; SCCmec Type; PFGE Profile; SCCmec Type Versus;
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摘要
Methicillin-resistant Staphylococcus aureus (MRSA) strains from Finland covering years 1997–1999 were studied for the presence of Panton-Valentine leukocidin (PVL) gene loci, and the clinically well-defined community-acquired MRSA (CA-MRSA) strains (n = 108) also for staphylococcal chromosomal cassette mec (SCCmec) and multilocus sequence types (MLST). Only a minority (12%) of the CA-MRSA strains contained the PVL gene loci and possessed genotypes formerly described as typical to CA-MRSA strains. The majority of these strains were heterogenous by MLST and pulsed-field gel electrophoresis (PFGE) analysis but, however, harboured the SCCmec cassette type IV. In conclusion, it seems doubtful to consider only molecular characteristics such as the presence of PVL genes as definite markers for CA-MRSA strains.
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页码:729 / 733
页数:4
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