Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders

被引：0
作者：
Markus Herberg Hovd
Espen Mariussen
Hilde Uggerud
Aslan Lashkarivand
Hege Christensen
Geir Ringstad
Per Kristian Eide
机构：
[1] University of Oslo,Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy
[2] Norwegian Institute for Air Research,Department of Neurosurgery
[3] Oslo University Hospital—Rikshospitalet,Institute of Clinical Medicine, Faculty of Medicine
[4] University of Oslo,Division of Radiology and Nuclear Medicine, Department of Radiology
[5] Oslo University Hospital—Rikshospitalet,Department of Geriatrics and Internal Medicine
[6] Sorlandet Hospital,Department of Air Quality and Noise
[7] Norwegian Institute of Public Health,undefined
来源：
Fluids and Barriers of the CNS | / 19卷
关键词：
Cerebrospinal fluid; Clearance; Gadobutrol; Brain metabolites; Intrathecal administration; Intrathecal drugs;
D O I：
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[1]  
Levey AS(2003)National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification Ann Intern Med 139 137-147
[2]  
Coresh J(2012)A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta Sci Transl Med 4 147ra111-341
[3]  
Balk E(2015)Structural and functional features of central nervous system lymphatic vessels Nature 523 337-56
[4]  
Kausz AT(2020)Glymphatic failure as a final common pathway to dementia Science 370 50-3219
[5]  
Levin A(2017)Understanding the functions and relationships of the glymphatic system and meningeal lymphatics J Clin Invest 127 3210-694
[6]  
Steffes MW(2020)Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis Nat Commun 11 4524-243
[7]  
Hogg RJ(2020)VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours Nature 577 689-275
[8]  
Perrone RD(2020)Meningeal lymphatic vessels regulate brain tumor drainage and immunity Cell Res 30 229-260
[9]  
Lau J(2019)Lymphatic outflow of cerebrospinal fluid is reduced in glioma Sci Rep 9 14815-418
[10]  
Eknoyan G(2020)Impaired meningeal lymphatic vessel development worsens stroke outcome J Cereb Blood Flow Metab 40 263-850
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