T-regulatory cell modulation: the future of cancer immunotherapy?
被引:0
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作者:
S Nizar
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机构:St George's University of London,Department of Cellular and Molecular Medicine
S Nizar
J Copier
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h-index: 0
机构:St George's University of London,Department of Cellular and Molecular Medicine
J Copier
B Meyer
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h-index: 0
机构:St George's University of London,Department of Cellular and Molecular Medicine
B Meyer
M Bodman-Smith
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h-index: 0
机构:St George's University of London,Department of Cellular and Molecular Medicine
M Bodman-Smith
C Galustian
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机构:St George's University of London,Department of Cellular and Molecular Medicine
C Galustian
D Kumar
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h-index: 0
机构:St George's University of London,Department of Cellular and Molecular Medicine
D Kumar
A Dalgleish
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机构:St George's University of London,Department of Cellular and Molecular Medicine
A Dalgleish
机构:
[1] St George's University of London,Department of Cellular and Molecular Medicine
[2] St Georges Hospital NHS Trust,Department of Colorectal Surgery
来源:
British Journal of Cancer
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2009年
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100卷
关键词:
T-regulatory;
tregs;
immunotherapy;
D O I:
暂无
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学科分类号:
摘要:
T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulating Treg activity in cancer patients.