Chromosome loops: SMC complexes as molecular cable ties?; [Chromosom in Schleifen: SMC-Kom - plexe als molekulare Kabelbinder?]

被引：0

作者：

Wilhelm L. ^{[1
]}

Gruber S. ^{[1
]}

机构：

[1] Chromosomale Organisation und Dynamik, Max-Planck-Institut für Biochemie, Am Klopferspitz 18, Martinsried

来源：

BIOspektrum | 2016年 / 22卷 / 4期

关键词：

D O I：

10.1007/s12268-016-0696-x

中图分类号：

学科分类号：

摘要：

Chromosome compaction is an essential prerequisite for the faithful segregation of chromosomes during cell division. SMC proteins promote the compaction and resolution of sister DNA molecules. They form ring-like structures that are thought to tie selected segments of chromosomes together. The underlying molecular mechanisms, however, are still poorly understood. Insights gained for the bacterial ancestor of SMC provide an excellent basis for our general understanding of these highly conserved molecular machines. © 2016, Springer-Verlag Berlin Heidelberg.

引用

页码：356 / 358

页数：2