S1PR1/S1PR3-YAP signaling and S1P-ALOX15 signaling contribute to an aggressive behavior in obesity-lymphoma

被引:0
作者
Xingtong Wang
Wei Guo
Xiaoju Shi
Yujia Chen
Youxi Yu
Beibei Du
Min Tan
Li Tong
Anna Wang
Xianying Yin
Jing Guo
Robert C. Martin
Ou Bai
Yan Li
机构
[1] University of Louisville,Department of Surgery, School of Medicine
[2] The First Hospital of Jilin University,Department of Hematology, Cancer Center
[3] The First Hospital of Jilin University,Department of Hepatobiliary and Pancreatic Surgery
[4] The First Hospital of Jilin University,Department of Gastrointestinal Surgery
[5] China-Japan Union hospital of Jilin University,Department of Cardiology
[6] Jilin University,Department of Epidemiology and Biostatistics, School of Public Health
来源
Journal of Experimental & Clinical Cancer Research | / 42卷
关键词
Lymphoma; Free fatty acid; S1P/SPHK signaling; Tumor microenvironment; Obesity;
D O I
暂无
中图分类号
学科分类号
摘要
• Obesity negatively impacted progression-free survival and overall survival in lymphoma patients while an aggressive tumor growth pattern was found in obesity-lymphoma mice.
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