Legionellosis presenting as singultus and external ophthalmoplegia

被引:0
作者
Shingo Konno
Haruhi Kono
Hisao Kitazono
Mayumi Murata
Hiroshi Nakazora
Nobuatsu Nomoto
Hideki Sugimoto
Ken Sanno
Toshiki Fujioka
机构
[1] Toho University Ohashi Medical Center,Division of Neurology, Department of Internal Medicine
[2] Toho University Ohashi Medical Center,Division of Respiratory, Department of Internal Medicine
来源
Neurological Sciences | 2012年 / 33卷
关键词
Legionellosis; Singultus; Abducens nerve palsy; Oligoclonal band; IgG index;
D O I
暂无
中图分类号
学科分类号
摘要
We report a 71-year-old man with legionellosis, who presented with abducens nerve palsy, singultus, confusion, memory impairment, ataxia, and hyporeflexia. Legionella pneumonia was diagnosed on the basis of detection of Legionella pneumophila antigen in the urine. The cerebrospinal fluid was negative for the antigen and antibody, but an oligoclonal band was detected, and the IgG index was elevated. It was speculated that an undetermined immune-mediated mechanism had contributed to the development of the neurological manifestations.
引用
收藏
页码:1435 / 1437
页数:2
相关论文
共 80 条
[1]  
Shetty KR(1980)Legionnaires’ disease with profound cerebellar involvement Arch Neurol 37 379-380
[2]  
Cilyo CL(1982)Neurological involvement in legionellosis J Neurol Neurosurg Psychiatry 45 603-608
[3]  
Starr BD(1984)Neurologic manifestations of Legionnaires’ disease Medicine 63 303-310
[4]  
Harter DH(1983)Neuropathologic evaluation of 40 confirmed cases of Legionella pneumonia Neurology 33 1340-1344
[5]  
Weir AI(2001)Detection of J Med Microbiol 50 509-516
[6]  
Bone I(1982) antigen in urine samples by the BinaxNOW immunochromatographic assay and comparison with both Binax Legionella urinary enzyme immunoassay (EIA) and biotest legionella urine antigen EIA Clin Chem 28 354-355
[7]  
Kennedy DH(2003)The cerebrospinal fluid immunoglobulin G index as a diagnostic aid in multiple sclerosis: a Bayesian approach Animus 38 8-161
[8]  
Johnson JD(2009)Oligoclonal band in Japanese Multiple Sclerosis N S W Public Health Bull 20 157-1171
[9]  
Raff MJ(2001)Diagnostic and typing methods for investigating Legionella infection Rev Neurol 32 896-2763
[10]  
Van Arsdall JA(1978)Third cranial nerve palsy and Legionnaire’s disease JAMA 240 1169-1578