TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination

被引：0
|
作者：
Hangqi Shen
Qiaoyun Gong
Jingting Zhang
Haiyan Wang
Qinghua Qiu
Jingfa Zhang
Dawei Luo
机构：
[1] Shanghai Jiao Tong University School of Medicine,Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital)
来源：
Eye and Vision | / 9卷
关键词：
Diabetic retinopathy; TRIM46; IκBα; Ubiquitination; NF-κB;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] VIP protects human retinal microvascular endothelial cells against high glucose-induced increases in TNF-α and enhances RvD1
    Shi, Haoshen
    Carion, Thomas W.
    Jiang, Youde
    Steinle, Jena J.
    Berger, Elizabeth A.
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2016, 123 : 28 - 32
  • [32] EGCG attenuates high glucose-induced endothelial cell inflammation by suppression of PKC and NF-κB signaling in human umbilical vein endothelial cells
    Yang, Jian
    Han, Yu
    Chen, Caiyu
    Sun, Hailan
    He, Duofen
    Guo, Jing
    Jiang, Baoquan
    Zhou, Lin
    Zeng, Chunyu
    LIFE SCIENCES, 2013, 92 (10) : 589 - 597
  • [33] LINC00963 silencing inhibits the proliferation and migration of high glucose-induced retinal endothelial cells via targeting miR-27b
    Zhang, Rui
    Niu, Chunhong
    Guan, Yuhan
    Wu, Jianhua
    Hu, Liping
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021, 22 (05)
  • [34] LncRNA H19inhibits high glucose-induced inflammatory responses of human retinal epithelial cells by targetingmiR-19b to increaseSIRT1expression
    Luo, Rong
    Li, Lan
    Hu, Yu-Xiang
    Xiao, Fan
    KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2021, 37 (02): : 101 - 110
  • [35] Inhibition of Cx43 gap junction uncoupling prevents high glucose-induced apoptosis and reduces excess cell monolayer permeability in retinal vascular endothelial cells
    Kim, Dongjoon
    Mouritzen, Ulrik
    Larsen, Bjarne Due
    Roy, Sayon
    EXPERIMENTAL EYE RESEARCH, 2018, 173 : 85 - 90
  • [36] Ginsenoside Rb1 Attenuates High Glucose-Induced Oxidative Injury via the NAD-PARP-SIRT Axis in Rat Retinal Capillary Endothelial Cells
    Fan, Chunlan
    Ma, Qing
    Xu, Meng
    Qiao, Yuan
    Zhang, Yi
    Li, Pin
    Bi, Yucong
    Tang, Minke
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (19)
  • [37] Connexin 43 (Cx43) upregulation rescues retinal endothelial cells from high glucose-induced apoptosis and excess permeability through amelioration of tight junctions
    Roy, S.
    Barrette, K.
    Tien, T.
    DIABETOLOGIA, 2013, 56 : S486 - S486
  • [38] Molecular mechanism of wedelolactone inhibits high glucose-induced human retinal vascular endothelial cells injury through regulating miR-190 expression
    Cai, Xiaojie
    Wang, Xiao
    Huang, Yuping
    Rao, Xiaopang
    MEDICINE, 2024, 103 (21) : E37388
  • [39] Geniposide inhibits high glucose-induced cell adhesion through the NF-κB signaling pathway in human umbilical vein endothelial cells
    Guang-fa Wang
    Shao-yu Wu
    Wei Xu
    Hong Jin
    Zheng-guang Zhu
    Zhong-huang Li
    Yuan-xin Tian
    Jia-jie Zhang
    Jin-jun Rao
    Shu-guang Wu
    Acta Pharmacologica Sinica, 2010, 31 : 953 - 962
  • [40] Astragaloside IV prevents high glucose-induced cell apoptosis and inflammatory reactions through inhibition of the JNK pathway in human umbilical vein endothelial cells
    You, Liangzhen
    Fang, Zhaohui
    Shen, Guoming
    Wang, Qin
    He, Ying
    Ye, She
    Wang, Liu
    Hu, Mengjie
    Lin, Yixuan
    Liu, Mengmeng
    Jiang, Aijuan
    MOLECULAR MEDICINE REPORTS, 2019, 19 (03) : 1603 - 1612
12345