Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer

被引：0
作者：
Sadanori Watanabe
Akitada Yogo
Tsuguteru Otsubo
Hiroki Umehara
Jun Oishi
Toru Kodo
Toshihiko Masui
Shigeo Takaishi
Hiroshi Seno
Shinji Uemoto
Etsuro Hatano
机构：
[1] Kyoto University,DSK Project, Medical Innovation Center, Graduate School of Medicine
[2] Cancer Research Unit,Department of Surgery, Graduate School of Medicine
[3] Sumitomo Pharma Co.,Department of Gastroenterology and Hepatology, Graduate School of Medicine
[4] Ltd,undefined
[5] Kyoto University,undefined
[6] Kyoto University,undefined
来源：
BMC Cancer | / 22卷
关键词：
Pancreatic cancer; Organoid; Peritoneal dissemination; Xenograft model; Compound screening;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 152 条
  • [1] Siegel RL(2021)Cancer statistics, 2021 CA Cancer J Clin 71 7-33
  • [2] Miller KD(2011)FOLFIRINOX versus gemcitabine for metastatic pancreatic Cancer N Engl J Med 364 1817-1825
  • [3] Fuchs HE(2013)Increased survival in pancreatic Cancer with nab-paclitaxel plus gemcitabine N Engl J Med 369 1691-1703
  • [4] Jemal A(2016)Pancreatic cancer Nat Rev Dis Prim 2 1-23
  • [5] Conroy T(2021)Treatment landscape of metastatic pancreatic cancer Cancer Treat Rev 96 102180-955
  • [6] Desseigne F(2019)Cancer modeling meets human organoid technology Science 364 952-338
  • [7] Ychou M(2015)Organoid models of human and mouse ductal pancreatic cancer Cell. 160 324-467.e6
  • [8] Bouché O(2018)Human pancreatic tumor organoids reveal loss of stem cell niche factor dependence during disease progression Cell Stem Cell 22 454-832
  • [9] Guimbaud R(2021)Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids Cell Stem Cell 28 816-26590
  • [10] Bécouarn Y(2019)Pancreatic cancer organoids recapitulate disease and allow personalized drug screening Proc Natl Acad Sci U S A 116 26580-1129
12345678910