Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis

被引:0
作者
Yulan Mo
Leanne L. Leung
Celia S. L. Mak
Xueyu Wang
Wai-Sun Chan
Lynn M. N. Hui
Hermit W. M. Tang
Michelle K. Y. Siu
Rakesh Sharma
Dakang Xu
Stephen K. W. Tsui
Hextan Y. S. Ngan
Mingo M. H. Yung
Karen K. L. Chan
David W. Chan
机构
[1] The University of Hong Kong,Department of Obstetrics & Gynaecology, LKS Faculty of Medicine
[2] The University of Hong Kong,Centre for PanorOmic Sciences Proteomics and Metabolomics Core, Li Ka Shing Faculty of Medicine
[3] Shanghai Jiao Tong University,Faculty of Medical Laboratory Science, Ruijin Hospital, School of Medicine
[4] The Chinese University of Hong Kong,School of Biomedical Sciences
[5] The Chinese University of Hong Kong-Shenzhen,School of Medicine
来源
Molecular Cancer | / 22卷
关键词
miR-141; Hippo/YAP1/pathway; Ovarian cancer; Tumor-stroma interactions; Peritoneal metastases; cancer-associated fibroblasts;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 494 条
[31]  
Salih Z(2009)Organotypic models of metastasis: a three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis Cancer Treat Res 149 335-179
[32]  
Kelly M(2014)miR-141 regulates colonic leukocytic trafficking by targeting CXCL12beta during murine colitis and human Crohn's disease Gut 63 1247-3733
[33]  
Said N(2019)MicroRNA-141-3p negatively modulates SDF-1 expression in age-dependent pathophysiology of human and murine bone marrow stromal cells J Gerontol A Biol Sci Med Sci 74 1368-448
[34]  
Ahmed N(2010)The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation Genes Dev 24 1106-38
[35]  
Stenvers KL(2015)Hippo component TAZ functions as a co-repressor and negatively regulates ΔNp63 transcription through TEA domain (TEAD) transcription factor J Biol Chem 290 16906-7259
[36]  
Tan DS(2021)An overview of signaling pathways regulating YAP/TAZ activity Cell Mol Life Sci 78 497-14269
[37]  
Agarwal R(2020)YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells Elife 9 e50770-3467
[38]  
Kaye SB(2017)DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-beta/SMAD4 signaling Oncogene 36 1404-1108
[39]  
Mikula-Pietrasik J(2019)New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments Theranostics 9 5332-2401
[40]  
Uruski P(2014)The chemokine receptors CXCR1 and CXCR2 regulate oral cancer cell behaviour J Oral Pathol Med 43 667-9