Free Radical Oxidation and Activity of Enzymes Catalyzing Biotransformation of Xenobiotics in the Liver of Rats with Experimental Acute Pancreatitis

被引：0
作者：
V. I. Shabanov
N. N. Sarbaeva
M. N. Milyakova
V. P. Detyuchenko
机构：
[1] Samara Military Medical Institute,Department of Surgery
来源：
Bulletin of Experimental Biology and Medicine | 2001年 / 132卷
关键词：
pancreatitis; liver; lipid peroxidation; antioxidant protection; detoxifying enzymes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The development of experimental acute pancreatitis in rats was accompanied by intensification of lipid peroxidation, activation of superoxide dismutase and glutathione reductase, inhibition of glutathione transferase, and deceleration of aniline N-hydroxylation by cytochrome P-450 in the liver. Antioxidants inhibited lipid peroxidation and antioxidant enzymes, but did not prevent inhibition of detoxifying enzymes.
引用
收藏
页码：754 / 756
页数：2
相关论文
共 14 条
[1]  
Prokop'eva N. V.(1999)undefined Vopr. Med. Khimii 45 321-325
[2]  
Gulyaeva L. F.(1996)undefined Byull. Eksp. Biol. Med. 121 26-29
[3]  
Polyakova N. E.(1998)undefined Dig. Dis. Sci. 43 2405-2410
[4]  
Khachatur'yan M. L.(1985)undefined Gen. Pharmacol. 16 13-18
[5]  
Gusakov V. M.(1969)undefined J. Biol. Chem. 244 6049-6055
[6]  
Komarov P. G.(undefined)undefined undefined undefined undefined-undefined
[7]  
Folch E.(undefined)undefined undefined undefined undefined-undefined
[8]  
Gelpi E.(undefined)undefined undefined undefined undefined-undefined
[9]  
Resello-Catafau J.(undefined)undefined undefined undefined undefined-undefined
[10]  
Closa D.(undefined)undefined undefined undefined undefined-undefined
12