Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence

被引:0
作者
Sjoerd H den Uil
Veerle M H Coupé
Janneke F Linnekamp
Evert van den Broek
Jeroen A C M Goos
Pien M Delis-van Diemen
Eric J Th Belt
Nicole C T van Grieken
Patricia M Scott
Louis Vermeulen
Jan Paul Medema
Herman Bril
Hein B A C Stockmann
Robert T Cormier
Gerrit A Meijer
Remond J A Fijneman
机构
[1] VU University Medical Center,Department of Pathology
[2] Spaarne Gasthuis,Department of Surgery
[3] VU University Medical Center,Department of Epidemiology and Biostatistics
[4] Laboratory of Experimental Oncology and Radiobiology,Department of Pathology
[5] Center for Experimental Molecular Medicine,Department of Surgery
[6] Academic Medical Center,Department of Biomedical Sciences
[7] The Netherlands Cancer Institute,Department of Pathology
[8] Albert Schweitzer Hospital,undefined
[9] University of Minnesota Medical School,undefined
[10] Spaarne Gasthuis,undefined
来源
British Journal of Cancer | 2016年 / 115卷
关键词
colorectal cancer; prognosis; biomarker; KCNQ1;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1565 / 1574
页数:9
相关论文
共 656 条
[1]  
Andre T(2009)Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial J Clin Oncol 27 3109-3116
[2]  
Boni C(2014)Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas Carcinogenesis 33 1487-1493
[3]  
Navarro M(2011)Prognostic role of cell cycle associated proteins in stage II and III colon cancer: a large cohort multimarker study Dis Col Rectum 54 E22-3211
[4]  
Tabernero J(2010)Lymph node negative colorectal cancers with isolated tumor deposits should be classified and treated as stage III Ann Surg Oncol 17 3203-1845
[5]  
Hickish T(2011)Loss of lamin A/C expression in stage II and III colon cancer is associated with disease recurrenece Eur J Cancer 47 1837-265
[6]  
Topham C(2014)Expression of apoptosis regulating proteins identifies stage ii and iii colon cancer patients with high risk of recurrence J Surg Oncol 109 255-1230
[7]  
Bonetti A(2012)High lymph node yield is related to microsatellite instability in colon cancer Ann Surg Oncol 19 1222-8340
[8]  
Clingan P(2005)Microsatellite Instability and colorectal cancer prognosis Clin Cancer Res 11 8332-3419
[9]  
Bridgewater J(2004)American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer J Clin Oncol 22 3408-76
[10]  
Rivera F(2013)Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer J Pathol 231 63-449