Evaluation of the impact of pharmacist-led medication reconciliation intervention: a single centre pre–post study from Ethiopia

被引：0
作者：
Alemayehu B. Mekonnen
Andrew J. McLachlan
Jo-anne E. Brien
Desalew Mekonnen
Zenahbezu Abay
机构：
[1] The University of Sydney,Faculty of Pharmacy
[2] Concord Hospital,Centre for Education and Research on Ageing
[3] University of New South Wales,St Vincent’s Hospital Clinical School, Faculty of Medicine
[4] Addis Ababa University,Department of Internal Medicine
[5] University of Gondar,Department of Internal Medicine
来源：
International Journal of Clinical Pharmacy | 2018年 / 40卷
关键词：
Ethiopia; Medication reconciliation; Medication safety; Medication errors; Pharmacists;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background The role of pharmacists in medication reconciliation (MedRec) is highly acknowledged in many developed nations. However, the impact of this strategy has not been well researched in low-and-middle-income countries, including Ethiopia. Objective The aim of this study was to investigate the impact of pharmacist-led MedRec intervention on the incidence of unintentional medication discrepancies in Ethiopia. Setting Emergency department in a tertiary care teaching hospital in Ethiopia. Method A single centre, prospective, pre-post study was conducted on adults (aged 18 years or over) that had been hospitalized for at least 24 h and were taking at least 2 home medications on admission. The intervention involved assignment of a pharmacist to an emergency care team so as to take the best possible medication history and reconcile this list with the current medications in use. Main outcome measure Incidence and potential clinical severity of unintentional medication discrepancies. Results 123 patients were included (pre-intervention, 49; post-intervention, 74). The proportion of patients with at least one unintended discrepancy was reduced from 59 to 10.5% after the intervention (p < 0.001). Similarly, the percentage of patients with potentially severe clinical impact medication discrepancies reduced significantly after the intervention (p < 0.01). Most importantly, the likelihood of occurrence of unintentional medication discrepancies was approximately 17 times more often in the absence of pharmacist intervention (OR 16.45, 95% CI 5.22, 51.85). Conclusion This study has found that pharmacist-led MedRec intervention was impactful, and it was able to minimize the incidence of unintentional medication discrepancies significantly.
引用
收藏
页码：1209 / 1216
页数：7
相关论文
共 136 条
  • [1] Rozich JD(2004)Standardization as a mechanism to improve safety in health care Jt Comm J Qual Saf 30 5-14
  • [2] Howard RJ(2010)Results of the Medications at Transitions and Clinical Handoffs (MATCH) study: an analysis of medication reconciliation errors and risk factors at hospital admission J Gen Intern Med 25 441-447
  • [3] Justeson JM(2008)Classifying and predicting errors of inpatient medication reconciliation J Gen Intern Med 23 1414-1422
  • [4] Macken PD(2008)Medication reconciliation at hospital discharge: evaluating discrepancies Ann Pharmacother 42 1373-1379
  • [5] Lindsay ME(2005)Unintended medication discrepancies at the time of hospital admission Arch Intern Med 165 424-429
  • [6] Resar RK(2005)Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review CMAJ 173 510-515
  • [7] Gleason KM(2012)Effect of a pharmacist intervention on clinically important medication errors after hospital discharge: a randomized trial Ann Intern Med 157 1-10
  • [8] McDaniel MR(2006)Medication reconciliation for reducing drug-discrepancy adverse events Am J Geriatr Pharmacother 4 236-243
  • [9] Feinglass J(2006)Role of pharmacist counseling in preventing adverse drug events after hospitalization Arch Intern Med 166 565-571
  • [10] Baker DW(2011)Impact of the Lund Integrated Medicines Management (LIMM) model on medication appropriateness and drug-related hospital revisits Eur J Clin Pharmacol 67 741-752
12345678910