Synthesis of substituted 1-[2-(adamantan-1-yl)ethyl]piperidines

被引：0
作者：
V. A. Shadrikova
E. V. Golovin
E. A. Kuznetsova
M. Yu. Rostova
Yu. N. Klimochkin
机构：
[1] Samara State Technical University,
来源：
Russian Journal of Organic Chemistry | 2016年 / 52卷
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摘要：
Quaternary 1-[2-(adamantan-1-yl)ethyl]pyridinium bromides were reduced with sodium tetrahydridoborate in ethanol, and hydroarylation of the resulting 1-[2-(adamantan-1-yl)ethyl]-1,2,3,6-tetrahydropyridines with benzene in trifluoromethanesulfonic acid afforded phenylpiperidines with preferentially equatorial orientation of the phenyl substituent.
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页码：1452 / 1462
页数：10
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