Local and Systemic Immune Responses to Intratracheal Instillation of Antigen and DNA Vaccines in Mice

被引：0

作者：

Catherine Lombry

Aline Marteleur

Mohammed Arras

Dominique Lison

Jamila Louahed

Jean-Christophe Renauld

Véronique Préat

Rita Vanbever

机构：

[1] Université catholique de Louvain (UCL),Department of Pharmaceutical Technology, School of Pharmacy

[2] School of Medicine,Industrial Toxicology and Occupational Medicine Unit

[3] UCL,undefined

[4] Ludwig Institute for Cancer Research and Experimental Medicine Unit,undefined

[5] UCL,undefined

来源：

Pharmaceutical Research | 2004年 / 21卷

关键词：

antigens and DNA vaccines; fate of vaccine molecule; IgG; intratracheal instillation; lungs; proliferation assay;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Purpose. The purpose of this study was to determine the immunization efficacy of antigen and DNA vaccines after delivery to the lung, to assess the integrity of the pulmonary tissue after vaccination, and to elucidate mechanisms involved in the induction of immunity.

引用

页码：127 / 135

页数：8