Upper abdominal obesity, insulin resistance and breast cancer risk

被引：0
|
作者：
BA Stoll
机构：
[1] St Thomas' Hospital,Oncology Department
来源：
International Journal of Obesity | 2002年 / 26卷
关键词：
abdominal obesity; adipocytes; breast cancer; hyperinsulinaemia; IGF-1; insulin resistance; oestrogen; PPAR gamma; visceral obesity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose: A majority of prospective studies show breast cancer risk to be higher in obese postmenopausal women with upper abdominal adiposity than in those with overall adiposity. The evidence is more limited and inconsistent in the case of premenopausal women. The review examines evidence that aberrant insulin signalling may be involved in the promotion of mammary carcinogenesis. The aetiology and concomitants of abdominal visceral obesity are examined.
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收藏
页码：747 / 753
页数：6
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