Therapeutic Drug Concentration Monitoring Using Saliva SamplesFocus on Anticonvulsants

被引:0
作者
Hua Liu
Mauricio R. Delgado
机构
[1] Texas Scottish Rite Hospital for Children,Department of Research
[2] Texas Scottish Rite Hospital for Children,Department of Neurology
来源
Clinical Pharmacokinetics | 1999年 / 36卷
关键词
High Performance Liquid Chromatography; Adis International Limited; Carbamazepine; Valproic Acid; Therapeutic Drug Monitoring;
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学科分类号
摘要
In the last 30 years there has been great interest in the use of saliva in therapeutic drug monitoring. Numerous investigators have suggested that saliva be used as an alternative body fluid for the therapeutic drug monitoring of anticonvulsant drugs. Not only can saliva be obtained easily on multiple occasions with minimal discomfort to the patient but, more importantly, useful relationships exist between the saliva and blood concentrations of the most commonly used anticonvulsant drugs.
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页码:453 / 470
页数:17
相关论文
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