Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19

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Chuang Guo
Mingming Wu
Beibei Huang
Rui Zhao
Linlin Jin
Binqing Fu
Ping Wang
Dongyao Wang
Meijuan Zheng
Jingwen Fang
Haiming Wei
Kun Qu
Fang Ni
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[1] University of Science and Technology of China,Department of Hematology, The First Affiliated Hospital of USTC, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine
[2] University of Science and Technology of China,Department of Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine
[3] University of Science and Technology of China,Institute of Immunology
[4] The First Affiliated Hospital of Anhui Medical University,Department of Clinical Laboratory
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Ageing; NK cell; Single-cell RNA-seq; Type-I interferon; COVID-19;
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