Does early sulfasalazine treatment provide long-term benefits to patients with juvenile idiopathic arthritis?

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作者
Tracy V Ting
Daniel J Lovell
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[1] OH,TV Ting is a 2nd year Pediatric Rheumatology Fellow and DJ Lovell holds the Joseph E Levinson Chair in Pediatric Rheumatology and is the Associate Director of the Division of Rheumatology at Cincinnati Children's Hospital Medical Center in Cincinnati
[2] USA.,undefined
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Nature Clinical Practice Rheumatology | 2008年 / 4卷
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The small, well-designed, observational study by van Rossum et al. raises and addresses questions of great significance for the treatment of children with JIA. The original RCT demonstrated significant benefits of sulfasalazine over placebo that, by today's standards, would be considered only moderate clinical improvement. Despite these initial modest effects, the sulfasalazine group demonstrated improved outcomes compared with the placebo group 9 years later.
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页码:344 / 345
页数:1
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