GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment

[31] Brandes AA(2011)Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair Cancer Res 71 2308-70

[32] Marosi C(2011)The Hedgehog’s tale: developing strategies for targeting cancer Nat Rev Cancer 11 493-100

[33] Bogdahn U(2014)EFEMP1 induces gamma-secretase/Notch-mediated temozolomide resistance in glioblastoma Oncotarget 5 363-34

[34] Van Meir EG(2010)The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance Clin Cancer Res 16 6060-68

[35] Hadjipanayis CG(2016)A Notch-Gli2 axis sustains Hedgehog responsiveness of neural progenitors and Muller glia Dev Biol 411 85-93

[36] Norden AD(2014)Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells Neuropathology 34 128-48

[37] Shu HK(2015)Transcription factor glioma-associated oncogene homolog 1 is required for transforming growth factor-beta1-induced epithelial-mesenchymal transition of non-small cell lung cancer cells Mol Med Rep 11 3259-undefined

[38] Wen PY(2014)Sonic hedgehog-Gli1 signaling pathway regulates the epithelial mesenchymal transition (EMT) by mediating a new target gene, S100A4, in pancreatic cancer cells PLoS One 9 e96441-undefined

[39] Olson JJ(2014)Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway Biochem Pharmacol 92 484-undefined

[40] Liu C-Y(2015)Sonic hedgehog-Gli1 signals promote epithelial-mesenchymal transition in ovarian cancer by mediating PI3K/AKT pathway Med Oncol 32 368-undefined

[31] Brandes AA(2011)Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair Cancer Res 71 2308-70

[32] Marosi C(2011)The Hedgehog’s tale: developing strategies for targeting cancer Nat Rev Cancer 11 493-100

[33] Bogdahn U(2014)EFEMP1 induces gamma-secretase/Notch-mediated temozolomide resistance in glioblastoma Oncotarget 5 363-34

[34] Van Meir EG(2010)The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance Clin Cancer Res 16 6060-68

[35] Hadjipanayis CG(2016)A Notch-Gli2 axis sustains Hedgehog responsiveness of neural progenitors and Muller glia Dev Biol 411 85-93

[36] Norden AD(2014)Epithelial-to-mesenchymal transition is involved in BCNU resistance in human glioma cells Neuropathology 34 128-48

[37] Shu HK(2015)Transcription factor glioma-associated oncogene homolog 1 is required for transforming growth factor-beta1-induced epithelial-mesenchymal transition of non-small cell lung cancer cells Mol Med Rep 11 3259-undefined

[38] Wen PY(2014)Sonic hedgehog-Gli1 signaling pathway regulates the epithelial mesenchymal transition (EMT) by mediating a new target gene, S100A4, in pancreatic cancer cells PLoS One 9 e96441-undefined

[39] Olson JJ(2014)Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway Biochem Pharmacol 92 484-undefined

[40] Liu C-Y(2015)Sonic hedgehog-Gli1 signals promote epithelial-mesenchymal transition in ovarian cancer by mediating PI3K/AKT pathway Med Oncol 32 368-undefined