Dissecting the pathobiology of altered MRI signal in amyotrophic lateral sclerosis: A post mortem whole brain sampling strategy for the integration of ultra-high-field MRI and quantitative neuropathology

被引：0
作者：
Menuka Pallebage-Gamarallage
Sean Foxley
Ricarda A. L. Menke
Istvan N. Huszar
Mark Jenkinson
Benjamin C. Tendler
Chaoyue Wang
Saad Jbabdi
Martin R. Turner
Karla L. Miller
Olaf Ansorge
机构：
[1] University of Oxford,Nuffield Department of Clinical Neurosciences
[2] University of Oxford,Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences
[3] University of Chicago,Department of Radiology
来源：
BMC Neuroscience | / 19卷
关键词：
Amyotrophic lateral sclerosis; Magnetic resonance imaging; brain; Systematic sampling; Histology; MRI-histology correlation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 567 条
[1]  
Kiernan MC(2011)Amyotrophic lateral sclerosis Lancet 377 942-955
[2]  
Vucic S(2016)The frontotemporal dementia-motor neuron disease continuum Lancet 388 919-931
[3]  
Cheah BC(2013)Mimics and chameleons in motor neurone disease Pract Neurol 13 153-164
[4]  
Turner MR(2015)What does imaging reveal about the pathology of amyotrophic lateral sclerosis? Curr Neurol Neurosci Rep 15 569-2555
[5]  
Eisen A(2014)Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis Brain 137 2546-969
[6]  
Hardiman O(2015)Quantitative susceptibility mapping (QSM) as a biomarker for C9orf72 familial ALS (P6.027) Neurology 84 P6-027-1092
[7]  
Burrell JR(2016)Magnetic susceptibility in the deep layers of the primary motor cortex in amyotrophic lateral sclerosis NeuroImage Clin 12 965-675
[8]  
Halliday GM(2015)Quantitative susceptibility mapping of the motor cortex in amyotrophic lateral sclerosis and primary lateral sclerosis Am J Roentgenol 204 1086-714
[9]  
Kril JJ(2012)Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 Tesla MRI and pathology PLoS ONE 7 e35241-439
[10]  
Ittner LM(2015)Histological-MRI correlation in the primary motor cortex of patients with amyotrophic lateral sclerosis J Magn Reson Imaging 41 665-120
12345678910