Cytotoxic effects of sesquiterpene lactones from the flowers ofHemisteptia lyrata B

被引:0
作者
Tae Joung Ha
Dae Sik Jang
Jong Rok Lee
Kyung Dong Lee
Jun Lee
Seon Woo Hwang
Hwa Jin Jung
Sang Hae Nam
Ki Hun Park
Min Suk Yang
机构
[1] Gyeongsang National University,Institute of Agriculture and Life Science
[2] Ewha Womans University,Graduate School of Molecular Life Sciences
[3] Gyeongsang National University,Department of Agricultural Chemistry, Division of Applied Life Science
[4] Chinju National University,Department of Food Processing
来源
Archives of Pharmacal Research | 2003年 / 26卷
关键词
Bunge; Sesquiterpene lactone; Aguerin B; 8α-Acetoxyzaluzanin C; Cynaropicrin; Deacylcynaropicrin; Cytotoxic activity;
D O I
暂无
中图分类号
学科分类号
摘要
Four guaia-12,6-olide type sesquiterpene lactones, aguerin B (1), 8α-acetoxyzaluzanin C (2), cynaropicrin (3), and deacylcynaropicrin (4), were isolated from the flowers ofHemisteptia lyrata Bunge. It is the first report on the isolation of compounds1-4 from Hemisteptia species. All the isolates (1-4) were examined for their cytotoxic activity against SK-OV-3, LOX-IMVI, A549, MCF-7, PC-3, and HCT-15 human cancer cell lines.
引用
收藏
页码:925 / 928
页数:3
相关论文
共 84 条
[1]  
Asakawa Y.(1979)Sesquiterpene lactones of Phytochemistry 18 285-288
[2]  
Takemoto T.(1978)Two sesquiterpene lactones from Phytochemistry 17 955-956
[3]  
Gonzalez A. G.(1992)The cytotoxicity of helenalin, its mono and difunctional esters, and related sesquiterpene lactones in murine and human tumor cells Drug Design Discovery 8 191-206
[4]  
Bermejo J.(2002a)Apigenin, tyrosinase inhibitor from the flowers of Agile. Chem. Biotechnol. 45 170-172
[5]  
Cabrera I.(2002b) Bunge Kor. J. Pharmacogn. 33 92-95
[6]  
Massanet G. M.(2002c)Studies on the constituents from the flowers of Heterocycles 57 151-155
[7]  
Mansilla H.(2003) Bunge II Heterocycles 60 623-629
[8]  
Galindo A.(1987)New guaiane-type sesquiterpene lactones from Pharmaceu. Sci. 4 509-514
[9]  
Grippo A. A.(1978) Bunge J. Pharm. Sci. 67 552-554
[10]  
Hall I. H.(1978)New sesquiterpene lactones from J. Pharm. Sci. 67 1235-1239