High Intensity Focused Ultrasound Ablation of Pancreatic Neuroendocrine Tumours: Report of Two Cases

被引：21

作者：

Orgera, Gianluigi ^{[1
]}

Krokidis, Miltiadis ^{[2
]}

Monfardini, Lorenzo ^{[1
]}

Bonomo, Guido ^{[1
]}

Della Vigna, Paolo ^{[1
]}

Fazio, Nicola ^{[3
]}

Orsi, Franco ^{[1
]}

机构：

[1] European Inst Oncol, Unit Intervent Radiol, I-20141 Milan, Italy

[2] St Thomas Hosp, Dept Radiol, London SE1 7EH, England

[3] European Inst Oncol, Div Med Oncol, I-20141 Milan, Italy

来源：

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY | 2011年 / 34卷 / 02期

关键词：

Interventional Radiology; Interventional Oncology; RADIOFREQUENCY ABLATION; INSULINOMA; PATIENT; EMBOLIZATION; CANCER;

D O I：

10.1007/s00270-010-9884-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe the use of ultrasound-guided high-intensity focused ultrasound (HIFU) for ablation of two pancreatic neuroendocrine tumours (NETs; insulinomas) in two inoperable young female patients. Both suffered from episodes of severe nightly hypoglycemia that was not efficiently controlled by medical treatment. After HIFU ablation, local disease control and symptom relief were achieved without postinterventional complications. The patients remained free of symptoms during 9-month follow-up. The lesions appeared to be decreased in volume, and there was decreased enhancing pattern in the multidetector computed tomography control (MDCT). HIFU is likely to be a valid alternative for symptoms control in patients with pancreatic NETs. However, currently the procedure should be reserved for inoperable patients for whom symptoms cannot be controlled by medical therapy.

引用

页码：419 / 423

页数：5

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