An integrated genome-wide association analysis on rheumatoid arthritis data

被引:0
作者
Jun Zhang
Xiaofeng Zhu
Richard S Cooper
机构
[1] University of Chicago,Department of Statistics
[2] Case Western Reserve University,Department of Epidemiology and Biostatistics
[3] Loyola University,Department of Preventive Medicine and Epidemiology
关键词
Population Stratification; Unaffected Sibling; Genetic Analysis Workshop; Affected Parent; Affected Sibling Pair;
D O I
10.1186/1753-6561-1-S1-S35
中图分类号
学科分类号
摘要
We propose a nonparametric association analysis combining both family and unrelated case-control genotype data. Under the assumption of Hardy-Weinberg equilibrium, we formed an affected group to compare with a group of unaffecteds.
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