Regulatory volume decrease in northern fur seal (Callorhinus ursinus) red blood cells

被引:0
|
作者
Ochiai H. [1 ]
Hishiyama N. [2 ]
Higa K. [2 ]
Koyama K. [3 ]
Seita M. [4 ]
Fujise H. [2 ]
机构
[1] Research Institute of Biosciences, Azabu University, Sagamihara, Kanagawa 229-8501
[2] Laboratory of Pathobiochemistry, School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa 229-8501
[3] Izu-Mito Sea Paradise, Numazu, Shizuoka 410-0223
[4] National Research Institute of Far Seas Fisheries, Fisheries Research Agency, Shizuoka, Shizuoka 424-8633
关键词
K-Cl cotransport; Na/Ca exchange; Northernfur seal; Red blood cells; Regulatory volume decrease;
D O I
10.1007/s00580-006-0643-1
中图分类号
学科分类号
摘要
The cation transport and regulatory volume decrease (RVD) were investigated in the red blood cells (RBCs) of northern fur seals (Callorhinus ursinus). Extracellular Ca-dependent Na efflux was increased to threefold by hypotonicity. K-Cl cotransport activity was not detected by hypotonic medium, but measured only by nitrite or N-ethylmaleimide stimulation. RBCs were restored to their original volume after being swollen in hypoosmotic medium with Ca, though this recovery was inhibited by the addition of quinidine. Based on these results, Na/Ca exchange transporter played the major role in the regulatory volume decrease in the RBCs of northern fur seals. © Springer-Verlag London Limited 2006.
引用
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页码:61 / 63
页数:2
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