Drug-resistant malaria: The era of ACT

被引：80
|
作者：
Lin J.T. [1 ]
Juliano J.J. [2 ]
Wongsrichanalai C. [3 ]
机构：
[1] Division of Infectious Diseases, Universityof North Carolina, School of Medicine, Chapel Hill
[2] Center for Infectious Diseases, University of North Carolina, CB7030, Chapel Hill, NC 27514
[3] Bangkok 10500
来源：
Current Infectious Disease Reports | 2010年 / 12卷 / 3期
关键词：
ACT; Antimalarial resistance; Artemisinin-based combination therapy; Drug-resistant malaria; Plasmodium falciparum;
D O I：
10.1007/s11908-010-0099-y
中图分类号：
学科分类号：
摘要：
As drug-resistant falciparum malaria has continued to evolve and spread worldwide, artemisinin-based combination therapies (ACT) have become the centerpiece of global malaria control over the past decade. This review discusses how advances in antimalarial drug resistance monitoring and rational use of the array of ACTs now available can maximize the impact of this highly efficacious therapy, even as resistance to artemisinins is emerging in Southeast Asia. © Springer Science+Business Media LLC 2010.
引用
收藏
页码：165 / 173
页数：8
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