Photodegradation Pathways of Protein Disulfides: Human Growth Hormone

被引:0
|
作者
Daniel Steinmann
Olivier Mozziconacci
Rupesh Bommana
John F. Stobaugh
Y. John Wang
Christian Schöneich
机构
[1] University of Kansas,Department of Pharmaceutical Chemistry
[2] Coriolis Pharma,Late Stage Pharmaceutical Development
[3] Biopharmaceutical Research and Development Service,undefined
[4] Merck Research Laboratories,undefined
[5] Genentech,undefined
来源
Pharmaceutical Research | 2017年 / 34卷
关键词
cross-link; disulfide; hGH; human growth hormone; oxidation; peptide cleavage; photo-degradation; somatotropin; thiyl radical;
D O I
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中图分类号
学科分类号
摘要
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页码:2756 / 2778
页数:22
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