Venous Irritation, Pharmacokinetics, and Tissue Distribution of Tirilazad in Rats Following Intravenous Administration of a Novel Supersaturated Submicron Lipid Emulsion

被引：0

作者：

Youmin Wang

Gebre-Mariam Mesfin

Carlos A. Rodríguez

John G. Slatter

Margaret R. Schuette

Andrea L. Cory

Michael J. Higgins

机构：

[1] Pharmacia & Upjohn,Pharmaceutical Development

[2] Pharmacia & Upjohn,Worldwide Toxicology Research

[3] Pharmacia & Upjohn,Clinical Pharmacokinetics

[4] Pharmacia & Upjohn,Drug Metabolism & Disposition Research

来源：

Pharmaceutical Research | 1999年 / 16卷

关键词：

submicron lipid emulsion; supersaturation; tirilazad; venous irritation; pharmacokinetics; tissue distribution;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Purpose. To compare the venous irritation, pharmacokinetics, and tissue distribution of tirilazad in rats after intravenous administration of a submicron lipid emulsion with that of an aqueous solution.

引用

页码：930 / 938

页数：8

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