Venous Irritation, Pharmacokinetics, and Tissue Distribution of Tirilazad in Rats Following Intravenous Administration of a Novel Supersaturated Submicron Lipid Emulsion

被引：0
|
作者：
Youmin Wang
Gebre-Mariam Mesfin
Carlos A. Rodríguez
John G. Slatter
Margaret R. Schuette
Andrea L. Cory
Michael J. Higgins
机构：
[1] Pharmacia & Upjohn,Pharmaceutical Development
[2] Pharmacia & Upjohn,Worldwide Toxicology Research
[3] Pharmacia & Upjohn,Clinical Pharmacokinetics
[4] Pharmacia & Upjohn,Drug Metabolism & Disposition Research
来源：
Pharmaceutical Research | 1999年 / 16卷
关键词：
submicron lipid emulsion; supersaturation; tirilazad; venous irritation; pharmacokinetics; tissue distribution;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To compare the venous irritation, pharmacokinetics, and tissue distribution of tirilazad in rats after intravenous administration of a submicron lipid emulsion with that of an aqueous solution.
引用
收藏
页码：930 / 938
页数：8
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