Osteoporosis.

被引:5
作者
Cimaz R. [1 ]
Biggioggero M. [1 ]
机构
[1] Department of Pediatrics, ICP, Clinica Pediatrica, Via Commenda 9, Milano
关键词
Bone Mineral Density; Osteoporosis; Bone Mass; Juvenile Idiopathic Arthritis; Alendronate;
D O I
10.1007/s11926-996-0005-7
中图分类号
学科分类号
摘要
Bone mass is determined primarily by genetic influences, but exogenous factors may also play a major role. The prevention of osteoporosis can start at childhood. Optimal achievement of peak bone mass during childhood and adolescence is important to minimize future fracture risk. Chronic inflammatory diseases can have a detrimental effect on bone mass through a variety of mechanisms. Different diagnostic methods for detecting osteoporosis (eg, dual x-ray absorptiometry, quantitative computed tomography, ultrasounds) are in use or under investigation. New treatment options are available; among these, the use of bisphosphonates seems to be the more promising approach.
引用
收藏
页码:365 / 370
页数:5
相关论文
共 113 条
[11]  
Vavrincova P(1998)Evaluation by dual x-ray absorptiometry (DXA) of bone mineral density in children with juvenile chronic arthritis Clin Exp Rheumatol 16 495-501
[12]  
Stepan J(1995)Reduced bone mineral content and normal serum osteocalcin in non-steroid-treated patients with juvenile rheumatoid arthritis Ann Rheum Dis 54 193-196
[13]  
Henderson CJ(2000)Bone mineral status in juvenile rheumatoid arthritis J Rheumatol 27 34-41
[14]  
Lovell DJ(1987)Vertebral collapse in juvenile chronic arthritis: its relationships with glucocorticoid therapy Calcif Tissue Int 41 75-78
[15]  
Hillman L(1994)Effects of nutritional supplementation on bone mineral status of children with rheumatic diseases receiving corticosteroid therapy J Rheumatol 21 530-535
[16]  
Cassidy JT(1996)Bone mineralization and bone mineral metabolism in children with juvenile rheumatoid arthritis Arthritis Rheum 39 746-757
[17]  
Johnson L(1998)Bone mineral density and turnover in children with systemic juvenile chronic arthritis J Rheumatol 25 990-992
[18]  
Hopp R(1998)Development of bone mineral density at the lumbar spine and femoral neck in juvenile chronic arthritis: a prospective one year follow-up study J Rheumatol 25 2450-2455
[19]  
Degan J(1999)Weight-bearing physical activity, calcium intake, systemic glucocorticoids, chronic inflammation, and body constitution as determinants of lumbar and femoral bone mineral in juvenile chronic arthritis Scand J Rheumatol 28 19-26
[20]  
Gallagher JC(1997)Predictors of total body bone mineral density in non-corticosteroidtreated prepubertal children with juvenile rheumatoid arthritis Arthritis Rheum 40 1967-1975