Relationship between body-mass index and serum folate concentrations in pregnant women

被引：0

作者：

H Kim

J-Y Hwang

K-N Kim

E-H Ha

H Park

M Ha

K-Y Lee

Y-C Hong

T Tamura

N Chang

机构：

[1] Ewha Wom,Department of Nutritional Science and Food Management

[2] a,Department of Preventive Medicine

[3] ns University,Department of Preventive Medicine

[4] Graduate School of Education,Department of Pediatrics

[5] Sangmyung University,Department of Preventive Medicine

[6] College of Medicine,undefined

[7] Ewha Wom,undefined

[8] an,undefined

[9] s University,undefined

[10] Dankook University College of Medicine,undefined

[11] Ulsan University Hospital,undefined

[12] Ulsan University College of Medicine,undefined

[13] Seoul National University College of Medicine,undefined

来源：

European Journal of Clinical Nutrition | 2012年 / 66卷

关键词：

folate; serum; body-mass index; pregnancy; human; malformations;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The concentration of micronutrients impacts fetal development and pregnancy outcome and has been suggested to be negatively correlated with the body-mass index (BMI). We evaluated the relationship between BMI and the serum folate concentration in 802 and 660 Korean pregnant women in mid- and late pregnancy, respectively, who participated in a multicenter prospective study. There was a significant negative correlation between BMI value and the serum folate concentration at mid- and late pregnancy (P for trend 0.001 and 0.024, respectively). A general linear model confirmed this correlation at both time points after adjusting for gestational age and total folate intake. These findings are important as the serum folate concentration is a rate-limiting factor for placental folate transport to the fetus, and an inadequate folate supply may cause various malformations.

引用

页码：136 / 138

页数：2

共 43 条

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