A contemporary review on pathogenesis and immunity of COVID-19 infection

被引:0
作者
Rasoul Mirzaei
Sajad Karampoor
Mohammad Sholeh
Pouya Moradi
Reza Ranjbar
Faezeh Ghasemi
机构
[1] Hamadan University of Medical Sciences,Department of Microbiology, School of Medicine
[2] Iran University of Medical Sciences,Department of Virology, School of Medicine
[3] Iran University of Medical Sciences,Department of Microbiology, School of Medicine
[4] Baqiyatallah University of Medical Sciences,Molecular Biology Research Center, Systems Biology and Poisonings Institute
[5] High Institute for Research and Education in Transfusion Medicine,Blood Transfusion Research Center
来源
Molecular Biology Reports | 2020年 / 47卷
关键词
Coronavirus; COVID-19; Viral accessory proteins; Viral receptors; Immune reactions; Cytopathic effects;
D O I
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中图分类号
学科分类号
摘要
Emerging of the COVID-19 pandemic has raised interests in the field of biology and pathogenesis of coronaviruses; including interactions between host immune reactions specific, and viral factors. Deep knowledge about the interaction between coronaviruses and the host factors could be useful to provide a better support for the disease sufferers and be advantageous for managing and treatment of the lung infection caused by the virus. At this study, we reviewed the updated information on the pathogenesis of the COVID-19 and the immune responses toward it, with a special focus on structure, genetics, and viral accessory proteins, viral replication, viral receptors, the human immune reactions, cytopathic effects, and host-related factors.
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收藏
页码:5365 / 5376
页数:11
相关论文
共 130 条
[1]  
Denison MR(2011)Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity RNA Biol 8 270-279
[2]  
Li G(2020)Coronavirus infections and immune responses J Med Virol 92 424-432
[3]  
Fehr AR(2015)Coronaviruses: an overview of their replication and pathogenesis Methods Mol Biol (Clifton, NJ) 1282 1-23
[4]  
Perlman S(2013)From SARS coronavirus to novel animal and human coronaviruses J Thorac Dis 5 S103-S108
[5]  
To KKW(2019)Recent aspects on the pathogenesis mechanism, animal models and novel therapeutic interventions for Middle East respiratory syndrome coronavirus infections Front Microbiol 10 569-269
[6]  
Skariyachan S(2020)A new coronavirus associated with human respiratory disease in China Nature 579 265-164
[7]  
Wu F(2011)Coronavirus pathogenesis Adv Virus Res 81 85-569
[8]  
Weiss SR(2020)Highlight of immune pathogenic response and hematopathologic effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 infection Front Immunol 11 1022-261
[9]  
Leibowitz JL(2019)Recent aspects on the pathogenesis mechanism, animal models and novel therapeutic interventions for middle east respiratory syndrome coronavirus infections Front Microbiol 10 569-1033
[10]  
Liang Y(2016)Structure, function, and evolution of coronavirus spike proteins Annu Rev Virol 3 237-261