In genetic control of disease, does 'race' matter?

被引：0

作者：

David B Goldstein

Joel N Hirschhorn

机构：

[1] University College London,Department of Biology at Galton Labs

[2] Divisions of Genetics and Endocrinology at Children's Hospital/Harvard Medical School,undefined

[3] Program in Medical and Population Genetics,undefined

[4] Broad Institute of MIT and Harvard University,undefined

来源：

Nature Genetics | 2004年 / 36卷

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摘要：

As geneticists begin to identify gene variants associated with common diseases and responses to treatment, it is increasingly important to determine whether these variants have consistent effects across different 'racial' or 'ethnic' groups. Until recently, too little was known about either disease genetics or pharmacogenetics to make a detailed assessment. Now, a new study reviewing 43 disease-associated gene variants suggests that the effects of gene variants may be largely consistent across different 'racial' or 'ethnic' groups.

引用

页码：1243 / 1244

页数：1

共 11 条

[1]

Ioannidis JPA(2004)undefined Nat. Genet. 36 1312-1318

[2]

Nitzani EE(1972)undefined Evol. Biol. 6 381-398

[3]

Trikalinos TA(2004)undefined Annu. Rev. Genomics Hum. Genet. 5 119-150

[4]

Lewontin RC(2004)undefined Genome Res. 14 1679-1685

[5]

Barbujani G(2003)undefined Nat. Rev. Genet. 4 937-947

[6]

Goldstein DB(undefined)undefined undefined undefined undefined-undefined

[7]

Serre D(undefined)undefined undefined undefined undefined-undefined

[8]

Pääbo S(undefined)undefined undefined undefined undefined-undefined

[9]

Goldstein DB(undefined)undefined undefined undefined undefined-undefined

[10]

Tate SK(undefined)undefined undefined undefined undefined-undefined

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