Critical review of SPECT imaging in pulmonary embolism

被引:6
作者
Stein P.D. [1 ,3 ]
Sostman H.D. [2 ]
Matta F. [1 ]
机构
[1] Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, MI
[2] Department of Radiology, Weill Cornell Medical College, New York, NY
[3] Michigan State University College of Osteopathic Medicine, 4707 St Antoine, Box 402, Detroit, 48201, MI
关键词
Pulmonary embolism; Single-photon emission computed tomography; Venous thromboembolism;
D O I
10.1007/s40336-014-0079-6
中图分类号
学科分类号
摘要
Outcome studies have shown that pulmonary embolism can be safely excluded in patients with negative ventilation/perfusion (V/Q) single-photon emission computed tomography (SPECT). The effective radiation dose of V/Q SPECT is much less than with computed tomographic (CT) pulmonary angiography, which would make it preferable to CT angiography in many young female patients. The accuracy of V/Q SPECT, however, is difficult to assess, because most published investigations are limited by incorporation bias or partial verification bias, as well as other limitations in study design and reporting. Consequently, the accuracy of V/Q SPECT relative to planar V/Q scintigraphy or CT angiography has not been definitively determined. There is need for a prospective investigation of the accuracy of V/Q SPECT with consecutive patients, blinded interpretations, and an independent reference standard, or independent composite reference standard. © 2014, Italian Association of Nuclear Medicine and Molecular Imaging.
引用
收藏
页码:379 / 390
页数:11
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