Clinical impact of albuminuria in diabetic nephropathy

被引：0
作者：
Takashi Wada
Miho Shimizu
Tadashi Toyama
Akinori Hara
Shuichi Kaneko
Kengo Furuichi
机构：
[1] Kanazawa University,Division of Nephrology, Department of Laboratory Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
[2] Kanazawa University,Division of Nephrology, Department of Disease Control and Homeostasis, Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
[3] Kanazawa University,Department of Disease Control and Homeostasis, Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
[4] Kanazawa University Hospital,Division of Blood purification
[5] Kanazawa University Hospital,Division of Nephrology
来源：
Clinical and Experimental Nephrology | 2012年 / 16卷
关键词：
Diabetic nephropathy; Albuminuria; Proteinuria; Glomerular filtration rate; Cardiovascular disease; Renal outcome;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Patients suffering from diabetic nephropathy, resulting in end-stage renal failure, are increasing in number. The pathophysiology of diabetic nephropathy remains to be fully investigated. In the clinical setting, the presence of albuminuria/overt proteinuria and a low glomerular filtration rate may predict poor renal prognosis, but the prognosis of the normoalbuminuric renally insufficient diabetic patient remains controversial. In addition to the measurement of urinary albumin excretion, biomarker studies to detect diabetic nephropathy more specifically at the early stage have been performed worldwide. There is a growing body of evidence for remission and/or regression of diabetic nephropathy, which may be an indicator for cardiovascular and renal risk reduction. Deeper insights into the pathological characteristics as well as the clinical impact of albuminuria on renal and cardiovascular outcome are required.
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页码：96 / 101
页数：5
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