A chloroplast proteostasis factor prevents aggregation of a human disease-related protein

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Nature Aging | 2023年 / 3卷
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Plants have an additional organelle to animals (the chloroplast), which means that they have a greater repertoire of protein homeostasis (proteostasis) mechanisms. We find that chloroplast proteostasis components prevent aggregation of a pathogenic fragment of human huntingtin expressed in plants, which reveals a potential avenue for therapeutic intervention in human proteinopathies.
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页码：1323 / 1324
页数：1
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