Following the pathway to Alzheimer’s disease

被引:0
|
作者
William Jagust
机构
[1] University of California,Helen Wills Neuroscience Institute
[2] Berkeley,undefined
来源
Nature Neuroscience | 2018年 / 21卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The human brain shows regional selective vulnerability to the pathology of Alzheimer’s disease. Jacobs et al. show that the protein amyloid-β promotes the spread of tau through specific components of a neural system underlying memory formation, thus leading to the prominent early symptom of amnesia.
引用
收藏
页码:306 / 308
页数:2
相关论文
共 50 条
  • [1] Following the pathway to Alzheimer's disease
    Jagust, William
    NATURE NEUROSCIENCE, 2018, 21 (03) : 306 - 308
  • [2] Alzheimer's disease:: the pharmacological pathway
    Allain, H
    Bentué-Ferrer, D
    Tribut, O
    Gauthier, S
    Michel, BF
    Drieu-La Rochelle, C
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2003, 17 (04) : 419 - 428
  • [3] Alzheimer's disease and the visual pathway
    Valenti, DA
    Laudate, TM
    Cronin-Golomb, A
    NEUROBIOLOGY OF AGING, 2004, 25 : S441 - S442
  • [4] The UFMylation pathway is impaired in Alzheimer's disease
    Yan, Tingxiang
    Heckman, Michael G.
    Craver, Emily C.
    Liu, Chia-Chen
    Rawlinson, Bailey D.
    Wang, Xue
    Murray, Melissa E.
    Dickson, Dennis W.
    Ertekin-Taner, Nilufer
    Lou, Zhenkun
    Bu, Guojun
    Springer, Wolfdieter
    Fiesel, Fabienne C.
    MOLECULAR NEURODEGENERATION, 2024, 19 (01)
  • [5] Kynurenine Pathway Metabolites in Alzheimer's Disease
    Giil, Lasse Melvaer
    Midttun, Oivind
    Refsum, Helga
    Ulvik, Arve
    Advani, Rajiv
    Smith, A. David
    Ueland, Per Magne
    JOURNAL OF ALZHEIMERS DISEASE, 2017, 60 (02) : 495 - 504
  • [6] The Amyloid-β Pathway in Alzheimer's Disease
    Hampel, Harald
    Hardy, John
    Blennow, Kaj
    Chen, Christopher
    Perry, George
    Kim, Seung Hyun
    Villemagne, Victor L.
    Aisen, Paul
    Vendruscolo, Michele
    Iwatsubo, Takeshi
    Masters, Colin L.
    Cho, Min
    Lannfelt, Lars
    Cummings, Jeffrey L.
    Vergallo, Andrea
    MOLECULAR PSYCHIATRY, 2021, 26 (10) : 5481 - 5503
  • [7] The Amyloid-β Pathway in Alzheimer’s Disease
    Harald Hampel
    John Hardy
    Kaj Blennow
    Christopher Chen
    George Perry
    Seung Hyun Kim
    Victor L. Villemagne
    Paul Aisen
    Michele Vendruscolo
    Takeshi Iwatsubo
    Colin L. Masters
    Min Cho
    Lars Lannfelt
    Jeffrey L. Cummings
    Andrea Vergallo
    Molecular Psychiatry, 2021, 26 : 5481 - 5503
  • [8] INVOLVEMENT OF THE KYNURENINE PATHWAY IN ALZHEIMER'S DISEASE
    Guillemin, G. J.
    Rahman, A.
    Ting, K.
    Cullen, K. M.
    Braidy, N.
    Chung, R. S.
    Wu, W.
    Brew, B. J.
    JOURNAL OF NEUROCHEMISTRY, 2010, 115 : 39 - 39
  • [9] Current diagnostic pathway for Alzheimer's disease
    Gorzkowska, Agnieszka
    Klimkowicz-Mrowiec, Aleksandra
    AKTUALNOSCI NEUROLOGICZNE, 2023, 23 (04): : 125 - 130
  • [10] Dysfunction of the magnocellular pathway in Alzheimer's disease
    Jacob, B
    Hache, JC
    Pasquier, F
    REVUE NEUROLOGIQUE, 2002, 158 (05) : 555 - 564