OASL1 inhibits translation of the type I interferon–regulating transcription factor IRF7

被引:0
作者
Myeong Sup Lee
Byungil Kim
Goo Taeg Oh
Young-Joon Kim
机构
[1] College of Life Science and Biotechnology,Department of Biochemistry
[2] Yonsei University,Division of Life and Pharmaceutical Sciences
[3] Ewha Women's University,Department of Integrated Omics for Biomedical Science
[4] WCU Program of Graduate School,undefined
[5] Yonsei University,undefined
来源
Nature Immunology | 2013年 / 14卷
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摘要
The production of type I interferon is regulated by the master transcription factor IRF7. Kim and colleagues show that OASL1 specifically recognizes IRF7 mRNA and inhibits its translation and the production of type I interferon.
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页码:346 / 355
页数:9
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