Efficient structural pseudoinverse learning-based hierarchical representation learning for skin lesion classification

The success of deep learning in skin lesion classification mainly depends on the ultra-deep neural network and the significantly large training data set. Deep learning training is usually time-consuming, and large datasets with labels are hard to obtain, especially skin lesion images. Although pre-training and data augmentation can alleviate these issues, there are still some problems: (1) the data domain is not consistent, resulting in the slow convergence; and (2) low robustness to confusing skin lesions. To solve these problems, we propose an efficient structural pseudoinverse learning-based hierarchical representation learning method. Preliminary feature extraction, shallow network feature extraction and deep learning feature extraction are carried out respectively before the classification of skin lesion images. Gabor filter and pre-trained deep convolutional neural network are used for preliminary feature extraction. The structural pseudoinverse learning (S-PIL) algorithm is used to extract the shallow features. Then, S-PIL preliminarily identifies the skin lesion images that are difficult to be classified to form a new training set for deep learning feature extraction. Through the hierarchical representation learning, we analyze the features of skin lesion images layer by layer to improve the final classification. Our method not only avoid the slow convergence caused by inconsistency of data domain but also enhances the training of confusing examples. Without using additional data, our approach outperforms existing methods in the ISIC 2017 and ISIC 2018 datasets.